SESSION 1: Welcome & Indication for Surgery and Surgical Options

 - How to Manage Small Renal Masses

 - Debate: Management of Patients with Positive Partial Nephrectomy Margins

 - Debate: Adjuvant Pembro in RCC: Don’t Put It in the Water

Lars     Lund    MD, DMSci
Cristina     Suárez Rodriguez    MD, PhD
Enrique     Trilla    MD, PhD
Axel    Bex    MD, PhD
Arnaud    Méjean    MD, PhD
Thomas    Powles    MD, MBBS, MRCP
Brian    Rini    MD

Recording

Session 2: Classifying RCC

 - A Panel Approach

 - Surgical Approach

 - Molecular Approach

 - Pathologist Approach

 - Oncologist Approach

Laurence    Albiges    MD, PhD
Ignacio    Duran    MD, PhD
Bradley    Leibovich    MD, PhD
Samra    Turajilic    MBBS, PhD
Ferran     Algaba Arrea    MD, PhD
Daniel    Heng    MD, MPH, FRCPC

Recording

Session 3: Pieter de Mulder Award Winner & Lecture

Lisa    Pickering    MD
Manuela    Schmidinger    MD

Recording

Session 4: Nonclear Cell RCC

 - Papillary RCC - Biology and Treatment

 - Chromophobe - Biology and Treatment

 - Translocation RCC - Biology and Treatment

 - FH Deficient Tumors RCC

Michael    Staehler    MD, PhD
Ulka     Vaishampayan    MBBS
Cristina     Suárez Rodriguez    MD, PhD
Martin    Voss    MD
Daniel    Heng    MD, MPH, FRCPC
Yüksel     Ürün    MD

Recording

Session 5: Patient Perspectives

Dawn Dyson 

Weronika Wrzesinski

Recording

Session 6: Oral Abstracts

 - ORAL ABSTRACT: An Integrated Clinicopathological-Molecular Classifier Optimizes Risk Stratification of Localised Clear Cell Renal Cell Carcinoma (ccRCC)

 - ORAL ABSTRACT: Exploring and identifying differences in characteristics and outcomes between patients receiving cabozantinib plus nivolumab (CaboNivo) and sunitinib in CheckMate 9ER (CM9ER): a latent class analysis

 - ORAL ABSTRACT: Extended follow-up of KEYNOTE-B61: First-line pembrolizumab plus lenvatinib for non–clear cell renal carcinoma (nccRCC)

 - ORAL ABSTRACT: Efficacy by baseline characteristics in the phase 3 LITESPARK-005 study of belzutifan versus everolimus for previously treated advanced clear-cell renal-cell carcinoma (ccRCC)

Cristina    Suárez Rodriguez    MD, PhD
David    McDermott    MD 
Zayd    Tippu    
David    Cella    PhD
Martin    Voss    MD
Laurence    Albiges    MD, PhD

Recording

Session 7: Debate: Systemic Therapy

 - KCA Updates

 - Debate: Combinations of Immune Checkpoint Inhibitors or IO TKI in Intermediate and Poor Risk Patients

 - Debate: IO Containing Therapy vs TKI Monotherapy in Favorable Risk Patients

 - Debate: What Should be the Comparator Arm for Future First-Line Trials?

Salvo    LaRosa    PhD
Samra    Turajlic    MBBS, PhD
Lisa     Pickering    MD
Laurence    Albiges    MD, PhD
Manuela    Schmidinger    MD
Samra    Turajlic    MBBS, PhD
Lisa     Pickering    MD
Cristina    Suárez Rodriguez    MD, PhD
Ignacio    Duran    MD, PhD

Recording

Session 8: Management Approaches of Low Volume and Oligometastatic RCC

 - The Role of Radiation Therapy in Localized Disease

 - Radiation Therapy in Oligometastatic Disease

 - The Role of Nephrectomy in Metastatic RCC

 - Treatment of Residual RCC Following First-Line Systemic Therapy

Manuela    Schmidinger    MD
Lars     Lund    MD, DMSci
Xavier    Maldonado    MD, PhD
Raquibul    Hannan    MD, PhD
Arnaud    Méjean    MD, PhD
Yüksel     Ürün    MD

Recording

Session 9: Oral Poster ad Presentations

 - Elevated soluble CD163 at baseline and increased PD1 expression on CD8pos T lymphocytes are associated with poor outcome in metastatic renal cell carcinoma.

 - Multi-omics and spatial architecture of antigenic macrophage-CD8+ T cell crosstalk at the core of immune checkpoint blockade (ICB) response in advanced clear-cell renal cell carcinoma (aRCC)

 - Patient-Derived Kidney Cancer Organoids to Predict Patient Therapeutic Responses

 - Evaluation of bone response in metastatic renal cell carcinoma treated in 1st line with immunotherapy-based therapy

 - Real-world characterization of patients treated with first-line checkpoint inhibitor-based combination therapy for advanced renal cell carcinoma: CARINA study post-hoc analysis

Lars     Lund    MD, DMSci
Mie    Wolff Kristensen    
"Lisa        
"    Kinget    
Isaac    Toleman    
Fabien    Moinard-Butot    D
Natalie    Charnley    MD

Recording

Session 10: Women & Allies in RCC

 - The Importance of Creating Gender-Inclusive Workplaces

Ulka    Vaishampayan    MBBS
Ann    Francke    

Recording

Session 12: Molecular Mechanism of RCC

-Mouse Models of Kidney Cancer

-Genetic Tumor Evolution

-Genetic Tumor Evolution

-Resistance to Immunotherapy

-Translating Insights from the TME Into Novel Therapies for Kidney Cancer

James Brugarolas, MD, PhD    
Samra Turajlic, MBBS, PhD
Charlotte Spencer, MBBS
David Braun, MD, PhD
David McDermott, MD, PhD

Recording

Session 14: Patient Advocacy - Implementation of Programs for Patients and Patient Organizations

-Unmet Need: Treating Bones Mets From Questions to Consensus

-How to Collect Data From Patient Experience

-Patient Perceptions and Engagement with Statistical Risk Models in RCC

Berit Eberhard
Juan Carlos Julian
Dena Battle

Recording

Vogelzang Award

Laurence    Abiges    MD, PhD

Bernard    Escudier    MD

Recording

Session 16: Novel Therapies/ Stem Cell/ Novel IO Approaches/ Static Session Beyond IO 

 - Beyond First-Line

 - Approvals Coming Soon

 - Novel Approaches

Maxine    Tran    MD, PhD, FRCS, MBBS
Guillermo     De Velasco    MD, PhD
Lisa    Pickering    MD 
Eric    Jonasch    MD
Andrew    Furness    MD, PhD

Recording

Session 17: Practice Changing Papers 

 - Paper 1: KN564

 - Paper 2: Contact 03

 - Paper 3: Cosmic 313 

Laurence    Abiges    MD, PhD
Ulka    Vaishampayan    MBBS
Laura     Bukavina    MD, MPH
Jean-Christophe    Bernhard    MD, PhD
Kate    Young    MBBS, MA, MD(Res.), MRCP
Viktor    Gruenwald    MD, PhD
Thomas    Powles    MD, MBBS, MRCP
Bernard    Escudier    MD

Recording

Session 18: WoodFire

Michael    Staehler    MD, PhD
Axel     Bex    MD, PhD
Camillo    Porta    MD  
Christian    Beisland    MD, PhD
Bernard    Escudier    MD
Rana    McKay    MD

Recording

Chairs Closing & Final Thoughts

Lars    Lund    MD, DMSci
Cristina    Suárez Rodriguez    MD, PhD

Recording